APLS Live signals | Maximize Profits with Getagraph.com

BUY 493 min ago

@ $37.45

Issued: 1 Jul 2024 @ 11:41

Return: -3.10%

Previous signal: Jun 28 - 15:44

Previous signal: Sell

Return: -0.69 %

Live Chart Being Loaded With Signals

Commentary (1 Jul 2024 @ 16:00):
Our systems believe the stock currently is undervalued by 0.17% compare to its pairs and should correct upwards.

Stats
Today's Volume	1.89M
Average Volume	1.45M
Market Cap	4.40B
EPS	$-0.540 ( Q1 \| 2024-05-07 )
Next earnings date	( $-0.320 ) 2024-07-29
Last Dividend	$0 ( N/A )
Next Dividend	$0 ( N/A )
P/E	-10.58 (Sector) 42.63 (Industry) 24.32
ATR14	$2.38 (6.54%)

AADI -2.74%

ABCL -6.08%

ABCM 0.04%

ABEO -0.94%

ABIO -0.78%

ABOS -1.45%

ABSI -2.27%

ABUS 0.97%

ABVX 2.57%

ACAD -1.29%

ACER -17.95%

ACET -4.96%

ACGN 1.29%

ACHL -1.60%

ACHV 1.70%

ACIU -0.25%

ACLX -2.88%

ACRV 1.03%

ACST -2.34%

ACXP -4.89%

ADAG -0.33%

ADAP 7.70%

ADGI 0.87%

ADIL -5.22%

ADMA 3.31%

ADPT -0.55%

ADTX 14.49%

ADVM 1.60%

ADXN -12.26%

AEON -0.95%

AEZS 3.07%

AFMD -0.73%

AGEN -0.36%

AGIO 0.60%

AGLE 6.66%

AGTC 0.00%

AIKI 0.85%

AIMDW -13.88%

AKBA -2.51%

AKRO -1.28%

AKTX 15.23%

AKUS 0.00%

ALBO 0.00%

ALDX -1.81%

ALEC -2.64%

ALGS 5.43%

ALKS 1.20%

ALLK -12.02%

ALLO 0.00%

ALLR 6.44%

ALNA 3.16%

ALNY 0.13%

ALPN 0.02%

ALPX 0.00%

ALRN 1.08%

ALT 8.27%

ALVR 0.93%

ALXN 0.00%

ALXO -0.66%

ALZN 0.91%

AMRN -0.29%

AMTI -3.13%

ANAB -1.80%

ANEB -1.83%

ANGN 0.00%

ANIX 0.45%

ANL -6.05%

ANNX 3.06%

ANPC -3.15%

APGE -1.96%

APGN 8.48%

APGNW 30.65%

APLM 0.96%

APLS -5.40%

APLT -1.28%

APM -7.51%

APOP 0.38%

APRE -0.98%

APTO -1.51%

APTX 3.17%

APVO 9.15%

ARAV -13.39%

ARCT -2.83%

ARDS 19.76%

ARDX 2.16%

ARGX 0.97%

ARNA 0.00%

ARPO -0.90%

ARQT 2.80%

ARTL -3.57%

ARTLW 0.00%

ARVN -2.40%

ARWR 0.23%

ASLN 0.00%

ASMB -3.50%

ASND -1.76%

ATAI 1.50%

ATHA -5.28%

ATHE 0.00%

ATHX -33.50%

ATNF -7.98%

ATOS 0.84%

ATRA -1.65%

ATXI -2.86%

ATXS 1.65%

AUPH -3.85%

AURA -2.51%

AUTL -0.29%

AVBP -2.16%

AVEO 0.00%

AVIR 1.81%

AVRO -1.41%

AVTE 2.41%

AVTX 1.12%

AVXL -2.61%

AXLA 0.00%

AXSM 0.66%

AYLA 0.00%

AZRX 2.07%

BBI 2.17%

BBIO -0.51%

BCAB -1.46%

BCDA 0.67%

BCDAW 0.00%

BCEL 0.00%

BCLI 5.47%

BCRX 7.93%

BCTX -4.39%

BCTXW 17.17%

BCYC 0.25%

BDRX -0.23%

BDTX 0.86%

BEAM -1.62%

BFRA -2.91%

BGNE 1.56%

BIOR -4.56%

BIVI 4.00%

BLCM -6.68%

BLI -5.88%

BLPH -1.93%

BLRX -1.06%

BLTE 0.31%

BLU 0.03%

BLUE -0.90%

BMEA -1.78%

BMRN -0.24%

BNOX -10.04%

BNTC 3.92%

BNTX -1.90%

BOLD 8.27%

BOLT -2.41%

BPMC 1.30%

BPTH -3.00%

BPTS -13.47%

BRNS 2.14%

BRTX -2.46%

BTAI -8.59%

BTTX -15.97%

BTX 0.05%

BVXV 0.74%

BXRX 7.39%

BYSI 2.92%

CABA 4.41%

CADL 1.61%

CALA 0.00%

CALC 7.32%

CALT -0.62%

CAPR 1.47%

CARA 1.94%

CARM 9.87%

CASI -1.82%

CATB -6.97%

CBAY 0.03%

CBIO -2.65%

CBLI -7.31%

CBUS -5.89%

CCCC 4.98%

CCXI 0.00%

CDAK 0.00%

CDIO -1.82%

CDIOW 6.00%

CDMO -0.28%

CDMOP 0.04%

CDT -6.12%

CDTTW 72.08%

CDTX 0.84%

CDXC -1.47%

CDXS -3.55%

CELC 1.59%

CELU 1.92%

CELUW 1.32%

CERC -1.68%

CERE 1.13%

CERO -8.16%

CEROW 43.57%

CFRX -27.95%

CGEM -4.07%

CGEN 4.17%

CGON 0.48%

CGTX 0.60%

CHMA -6.00%

CHRS -6.94%

CINC 0.00%

CING 7.50%

CINGW 4.85%

CKPT -4.65%

CLBS -16.75%

CLDX 5.35%

CLGN 1.00%

CLLS 3.48%

CLNN 0.22%

CLNNW 44.05%

CLRB 2.00%

CLSD -4.62%

CLSN -0.68%

CLVS 0.00%

CMMB 5.00%

CMND -1.19%

CMPI 0.00%

CMPX -5.45%

CMRA 0.00%

CMRAW 33.33%

CMRX -0.80%

CNCE 0.00%

CNSP -10.13%

CNST 0.00%

CNTA -2.55%

CNTB -5.26%

CNTX -9.73%

COCP 3.00%

COEPW 0.00%

COGT 6.05%

CORT 0.55%

COYA 0.66%

CPRX 1.81%

CRBP 9.17%

CRBU -3.05%

CRDF -7.66%

CRGX -2.56%

CRIS -7.54%

CRNX 2.86%

CRSP -0.11%

CRTX 2.63%

CRVO -5.84%

CRVS 1.65%

CSBR -4.26%

CTCX 23.31%

CTIC 0.06%

CTMX 9.02%

CTNM 19.25%

CTXR -6.92%

CUE -17.74%

CVAC -2.06%

CVKD -1.15%

CWBR 0.00%

CYAD -12.96%

CYCC 0.00%

CYCCP -11.68%

CYCN 0.88%

CYT -2.27%

CYTK 0.96%

CYTO 9.91%

DARE -6.03%

DAWN -1.45%

DBTX -0.81%

DBVT 2.20%

DFFN 10.28%

DICE 0.06%

DMAC 0.00%

DNLI -5.21%

DNTH 11.55%

DOMH 4.81%

DRMA -5.37%

DRMAW 7.69%

DRNA 0.00%

DRTS 0.79%

DRTSW 19.05%

DRUG -2.77%

DSGN -2.99%

DTIL 1.64%

DYAI 3.38%

EARS -1.77%

EDIT -1.28%

EDSA 2.09%

EFTR -8.00%

EFTRW -41.67%

EIGR -9.21%

ELAB 0.07%

ELDN -4.92%

ELEV 5.93%

ELOX 1.45%

ELTX -8.03%

ELVN -2.87%

ELYM -0.84%

ENGN -4.03%

ENGNW -2.88%

ENLV -2.82%

ENOB 1.79%

ENSC -1.23%

ENTA 0.77%

ENTO -11.11%

ENTX -4.35%

ENVB -5.90%

EPIX -2.66%

EPRX 2.38%

EPZM 0.00%

EQ -2.21%

EQRX -2.09%

EQRXW 0.00%

ERAS 3.39%

ERNA 4.14%

ERYP 1.30%

ESLA 4.76%

ESLAW 0.00%

ETNB -3.12%

ETON 3.34%

ETTX 0.00%

EVAX 0.70%

EVGN -0.91%

EVLO 39 899.32%

EWTX 7.61%

EXAI 0.98%

EXEL -0.98%

EYEG -0.51%

EYEN 14.27%

EYPT -4.48%

FATE -0.61%

FBIO -1.17%

FBIOP 0.70%

FBLG -19.84%

FBRX 1.68%

FDMT 1.67%

FENC 2.62%

FGEN -13.69%

FHTX 1.57%

FIXX 0.77%

FMTX 0.00%

FNCH -10.95%

FOLD -1.21%

FREQ 4.76%

FRLN 0.15%

FRTX -4.21%

FSTX 0.00%

FTRE 2.23%

FULC 1.77%

FUSN 0.00%

FWBI 4.59%

FWP 0.00%

GALT 3.98%

GANX -12.50%

GBIO -8.87%

GBT 0.01%

GDTC -0.99%

GERN 2.36%

GHRS 0.77%

GLMD -1.01%

GLPG 0.93%

GLSI -2.84%

GLTO -1.73%

GLUE 5.35%

GLYC 5.15%

GMAB -1.11%

GMDA -18.25%

GMTX 0.00%

GNCA -85.71%

GNFT 10.80%

GNLX -5.64%

GNPX 2.39%

GNTA -0.87%

GOSS 5.18%

GOVX 2.98%

GOVXW -10.37%

GPCR 1.86%

GRAY -10.80%

GRCL 0.05%

GRNA -0.03%

GRNAW 8.91%

GRPH -2.75%

GRTS -6.13%

GRTX -8.63%

GTHX 8.33%

GUTS 4.45%

GXGXW 41.67%

GYRE 0.92%

HALO -0.65%

HARP 0.09%

HCWB 0.46%

HEPA -0.93%

HGEN -84.62%

HILS 5.66%

HLVX -0.28%

HOOK 6.17%

HOTH -1.12%

HOWL -3.69%

HRMY 0.83%

HRTX -0.86%

HSTO 0.00%

HUMA 11.88%

HUMAW 22.30%

IBRX -0.79%

ICCC -8.04%

ICPT 0.21%

ICU 23.06%

ICUCW 13.26%

ICVX -0.91%

IDRA -23.04%

IDYA 2.31%

IFRX -1.72%

IGMS -1.16%

IKNA 0.00%

IKT -5.34%

IMAB -2.99%

IMCR 7.49%

IMGN 0.02%

IMGO 0.00%

IMMP 0.00%

IMMX 7.07%

IMNM 0.83%

IMNN 8.62%

IMPL -27.27%

IMRA 15.96%

IMRN -9.26%

IMRX -8.59%

IMTX 3.27%

IMTXW 27.41%

IMUX 0.90%

IMV 0.00%

IMVT 4.20%

INAB -3.95%

INBX -3.03%

INCY 0.41%

INDP 4.25%

INFI -52.38%

INKT -3.51%

INM -5.24%

INMB -4.54%

INO 6.56%

INSM -0.99%

INTS 0.41%

INVA 0.61%

INZY -1.12%

IOBT -4.27%

IONS -1.15%

IOVA 0.50%

IPA -3.71%

IPHA 7.22%

IPSC -5.49%

IRON 3.11%

ISEE 0.38%

ITOS 1.15%

ITRM -5.60%

IVA -1.19%

IVVD 9.09%

JAGX -2.79%

JANX -0.41%

JAZZ -0.24%

JNCE 0.00%

JSPR 1.94%

JSPRW 5.15%

JUNS 0.00%

JUNSW 0.00%

KA 4.20%

KALV 0.93%

KDNY 0.22%

KMPH -0.34%

KNSA -3.59%

KNTE -0.38%

KOD 0.85%

KPRX 3.57%

KPTI -6.01%

KRBP -1.83%

KRON -9.68%

KROS -4.22%

KRRO -0.06%

KRTX 0.03%

KRYS -0.75%

KTRA 10.14%

KTTA 0.38%

KTTAW 1.83%

KURA 2.96%

KYMR 3.69%

KYTX 4.13%

KZIA -4.91%

KZR -2.73%

LABP 0.57%

LBPH 14.39%

LBPS 0.00%

LBPSW 14.81%

LEGN 3.91%

LENZ 2.31%

LEXX -0.72%

LEXXW 23.90%

LGND 0.70%

LGNDV 0.00%

LGVN -2.48%

LIAN -8.28%

LIFE 2.70%

LIPO -3.41%

LIXT -0.38%

LIXTW -3.71%

LJPC -0.32%

LMNL 0.12%

LOGC -3.15%

LPCN -6.31%

LPTX -4.59%

LQDA 0.33%

LRMR 13.66%

LSTA 2.31%

LTRN -3.21%

LUMO -2.46%

LVTX 3.89%

LXEO -2.68%

LXRX -0.30%

LYEL 8.97%

LYRA 7.30%

MACK 0.10%

MBIO 2.41%

MBRX -1.15%

MCRB -0.25%

MDGL -0.30%

MDNA -13.16%

MDWD -0.84%

MDXG -3.32%

MEIP -2.06%

MESO -0.44%

MGNX 1.18%

MGTA -7.74%

MGTX -2.61%

MGX 8.33%

MIRM -0.09%

MIRO 0.59%

MIST 0.75%

MITO 0.00%

MLEC -0.88%

MLECW -31.50%

MLND -5.36%

MLTX -4.94%

MLYS 4.02%

MNKD -2.49%

MNMD -1.94%

MNOV 0.00%

MNPR -0.88%

MOLN 2.80%

MOR -0.22%

MORF -4.46%

MREO 0.83%

MRKR -0.74%

MRNA -2.36%

MRNS 9.40%

MRSN -1.99%

MRTX -0.17%

MRUS -7.98%

MRVI -3.07%

MTCR -1.29%

MTEM 2.61%

MTP -18.50%

MURA -0.96%

MYMD 0.00%

NAMS 7.13%

NAMSW -4.76%

NAUT -2.99%

NBRV 0.71%

NBSE -1.56%

NBTX 7.00%

NCNA 7.36%

NERV -0.86%

NEXI -6.90%

NGM -1.28%

NGNE 11.62%

NKGN 0.00%

NKGNW -12.00%

NKTR -1.61%

NKTX -1.02%

NLSP -9.50%

NLSPW 26.58%

NMRA 1.12%

NMTR -42.97%

NOVN -24.84%

NRBO -6.20%

NRIX 0.19%

NRSN -3.57%

NRSNW -2.91%

NRXP 5.74%

NRXPW 41.43%

NRXS 1.44%

NTBL -6.12%

NTEC -12.45%

NTHI 0.00%

NTLA 0.40%

NTRBW 74.65%

NUVL -0.46%

NVAX 0.55%

NVCT -2.37%

NVIV -34.28%

NXTC -5.66%

NYMX -0.05%

OABI -0.27%

OABIW -9.28%

OBIO -12.64%

OBSV 0.00%

OCEA -3.28%

OCGN 4.84%

OCS -0.50%

OCUL -2.63%

OCUP 3.92%

ODT -4.27%

OKYO 1.64%

OLMA 2.96%

OMER -2.71%

OMGA 8.70%

ONCO -6.10%

ONCR -3.08%

ONCS 31.87%

ONCT -7.70%

ONCY 0.53%

ONTX -0.47%

ONVO -0.34%

OPNT 0.00%

OPT -0.99%

ORGS 8.13%

ORIC 8.06%

ORMP -0.39%

ORPH 0.00%

ORTX 0.30%

OSMT -1.77%

OTIC -92.64%

OTLK 0.41%

OVID 12.09%

OYST 0.00%

PALI -5.29%

PASG 11.43%

PBLA -10.00%

PBM 6.33%

PBYI 0.61%

PCSA -7.11%

PCVX 1.89%

PDSB 3.41%

PEPG 12.22%

PGEN -1.90%

PHAR -4.62%

PHAS 0.00%

PHAT 4.95%

PHIO -3.88%

PHIOW 36.47%

PHVS -0.59%

PHXM -5.20%

PIRS -1.82%

PKBO 0.00%

PKBOW 999 900.00%

PLRX 1.02%

PLUR -0.43%

PMN 6.67%

PMVP -2.47%

PNT 0.16%

PPBT -13.47%

PRAX -0.41%

PRDS 0.93%

PRLD -1.05%

PROG -3.47%

PROK 1.63%

PRQR -0.60%

PRTA -0.78%

PRTC 3.68%

PRTG -7.63%

PRTK 1.83%

PRVB 0.00%

PSTI -2.91%

PSTV 2.04%

PSTX 3.08%

PTCT 1.93%

PTE -0.82%

PTGX 1.59%

PTIXW -48.41%

PULM 1.55%

PXMD -1.27%

PYPD -0.24%

PYXS -3.32%

QLGN -3.77%

QNCX -3.33%

QNRX 1.75%

QSI -11.01%

QSIAW 4.08%

QTTB 5.74%

QURE -0.78%

RAIN -1.63%

RANI 0.53%

RAPT -5.57%

RARE 0.05%

RCKT -4.04%

REGN 0.57%

RENB -10.86%

REPL 4.00%

RETA 0.02%

REUN -0.89%

REVB -1.58%

REVBU 3.46%

REVBW 0.00%

RGLS 6.44%

RGNX -5.38%

RIGL 2.31%

RLAY -1.84%

RLMD 2.33%

RLYB 1.49%

RNA 1.05%

RNAC -10.14%

RNAZ -4.54%

RNXT 1.77%

ROIV 2.46%

ROIVW 4.56%

RPHM 2.65%

RPRX -0.68%

RPTX 0.91%

RUBY 2.70%

RVLP -32.05%

RVMD 0.00%

RVMDW -1.40%

RVNC 0.00%

RVPH -7.03%

RVPHW 4.88%

RXDX 0.09%

RXRX -0.53%

RYTM 3.92%

RYZB 0.02%

RZLT 0.23%

SABS -1.94%

SABSW 54.57%

SAGE 1.57%

SANA 0.18%

SAVA -1.70%

SAVAW 0.00%

SBBP 1.52%

SBTX 1.03%

SCNI 3.16%

SCPH -0.69%

SCPS 0.00%

SEEL 3.69%

SEER 0.60%

SELB -8.00%

SESN 7.29%

SGEN -0.07%

SGMO -7.90%

SGMT -7.60%

SGTX -2.56%

SIOX 22.63%

SLDB 10.58%

SLGL -4.21%

SLN -1.37%

SLNO 3.65%

SLRX -7.92%

SLS -0.84%

SMMT 4.36%

SNDX 4.87%

SNGX -4.26%

SNPX 1.97%

SONN -0.80%

SPPI -0.49%

SPRB 2.55%

SPRC -5.98%

SPRO -1.54%

SRNE -20.00%

SRPT -0.79%

SRRA 0.00%

SRRK -2.40%

SRZN -2.28%

STAB 0.00%

STOK 2.66%

STRO 4.10%

STSA 0.00%

STTK 3.37%

SURF -0.93%

SVRA 15.14%

SWTX 2.28%

SYBX -0.67%

SYRS -4.46%

TALS -0.73%

TARA 0.48%

TARS 3.90%

TBPH 0.47%

TCBP 1.76%

TCDA 0.00%

TCON -30.63%

TCRR 0.00%

TCRT -6.87%

TCRX 1.37%

TECH -0.06%

TENX -1.32%

TERN 0.59%

TFFP 7.23%

TGTX 2.02%

THRX 0.12%

TIL 0.10%

TLC 0.00%

TLSA -3.63%

TNGX 4.90%

TNXP 4.96%

TNYA 8.71%

TPST -2.28%

TRDA 0.49%

TRVI -3.02%

TRVN -3.81%

TSHA 0.89%

TSVT 5.19%

TTNP -0.18%

TVTX 0.73%

TYRA 8.07%

UBX -1.48%

UNCY 7.76%

URGN -1.79%

UTHR 0.14%

VACC 11.36%

VALN -3.27%

VAXX 20.24%

VBIV 4.85%

VBLT -8.77%

VCEL -1.85%

VCNX -0.15%

VCYT -1.57%

VERA 0.30%

VERU 4.45%

VERV 2.05%

VIGL 9.25%

VINC -6.26%

VIR 2.25%

VIRI 3.26%

VIRX -6.20%

VKTX 4.36%

VLON -13.04%

VNDA -1.24%

VOR -1.07%

VRCA 9.05%

VRDN 1.54%

VRNA 7.26%

VRPX -1.59%

VRTX 0.54%

VSTM 9.06%

VTGN 2.59%

VTVT -0.42%

VTYX -2.16%

VXRT 3.19%

VYGR -0.63%

VYNE -2.54%

VYNT 7.78%

WINT 0.00%

WVE 4.91%

XBIO -0.48%

XBIT 7.98%

XCUR -3.93%

XENE -3.33%

XERS -3.56%

XFOR 1.62%

XLO -2.49%

XLRN 0.00%

XNCR 0.48%

XOMA 5.11%

XOMAO 0.20%

XOMAP 1.98%

XRTX -1.06%

YMAB -2.07%

ZGNX 0.00%

ZIOP -0.88%

ZLAB -0.23%

ZNTL 2.45%

ZSAN 0.00%

Insider Trading

Date	Person	Action	Amount	type
2024-06-28	Dunlop A. Sinclair	Buy	900	Common Stock
2024-06-28	Dunlop A. Sinclair	Sell	900	Stock Option (Right to Buy)
2024-06-21	Dunlop A. Sinclair	Sell	35 305	Common Stock
2024-06-21	Dunlop A. Sinclair	Sell	1 695	Common Stock
2024-05-20	Deschatelets Pascal	Buy	24 500	Common Stock

INSIDER POWER
-18.46
Last 100 transactions
Buy: 830 336 \| Sell: 1 166 383

Correlation (AI algo v.1.1b): Undervalued: 0.17% $36.47 paired level. (The Algo Track The Changes Of The Most Correlated Stocks In Realtime And Give An Instant Update)

Volume Correlation

Long: -0.91 (very strong negative)

Short: -0.92 (very strong negative)

Signal:(39) Neutral

Apellis Pharmaceuticals Correlation

10 Most Positive Correlations
OZEM	1
DLHC	0.954
MPAA	0.943
APDN	0.942
MBIO	0.935
JACK	0.933
ALGT	0.933
SHLS	0.932
TOI	0.931
APVO	0.929

10 Most Negative Correlations
VCTR	-0.945
BNTC	-0.941
AEYE	-0.94
NKTR	-0.939
SMTC	-0.938
KALU	-0.935
FRLA	-0.931
RVMD	-0.929
CGBD	-0.928
GGAL	-0.928

Did You Know?

Correlation is a statistical measure that describes the relationship between two variables. It ranges from -1 to 1, where -1 indicates a perfect negative correlation (as one variable increases, the other decreases), 1 indicates a perfect positive correlation (as one variable increases, the other increases), and 0 indicates no correlation (there is no relationship between the variables).

Correlation can be used to analyze the relationship between any two variables, not just stocks. It's commonly used in fields such as finance, economics, psychology, and more.

Apellis Pharmaceuticals Correlation - Currency/Commodity

0.65
( weak )

0.00
( neutral )

-0.10
( neutral )

-0.70
( moderate negative )

0.15
( neutral )

Apellis Pharmaceuticals Financials

Annual	2023
Revenue:	$396.59M
Gross Profit:	$336.38M (84.82 %)
EPS:	$-4.45

FY	2023
Revenue:	$396.59M
Gross Profit:	$336.38M (84.82 %)
EPS:	$-4.45

FY	2022
Revenue:	$75.42M
Gross Profit:	$69.79M (92.53 %)
EPS:	$-6.15

FY	2021
Revenue:	$66.56M
Gross Profit:	$61.36M (92.19 %)
EPS:	$-8.84

Financial Reports:

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Apellis Pharmaceuticals Options Data

Calls

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Puts

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Apellis Pharmaceuticals

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company's lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glomerulopathy (C3G), and immune complex membranoproliferative glomerulonephritis (IC-MPGN) in nephrology; and amyotrophic lateral sclerosis (ALS) in neurology. In addition, the company develops APL-2006, a bispecific C3 and VEGF inhibitor for treating complement-mediated disorders; APL-1030, a C3 inhibitor for the treatment of multiple neurodegenerative diseases; and the combination of EMPAVELI and a small interfering RNA, or siRNA for reducing the production of C3 proteins by the liver. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) to co-develop pegcetacoplan; and a research collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is based in Waltham, Massachusetts.