APLS实时信号 | 通过Getagraph.com最大化利润

出售 34 min ago

@ $40.91

发出时间: 26 Jun 2024 @ 23:54

回报率: -1.03%

上一信号: Jun 26 - 21:34

上一信号: 购买

回报率: 2.02 %

Live Chart Being Loaded With Signals

Commentary (27 Jun 2024 @ 00:28):
Our systems believe the stock currently is overvalued by -0.20% compare to its pairs and should correct downwards.

Stats
今日成交量	341 507
平均成交量	1.40M
市值	4.91B
EPS	$-0.540 ( Q1 \| 2024-05-07 )
下一个收益日期	( $-0.320 ) 2024-07-29
Last Dividend	$0 ( N/A )
Next Dividend	$0 ( N/A )
P/E	-11.80 (Sector) 42.63 (Industry) 24.32
ATR14	$1.190 (2.94%)

AADI -3.24%

ABCL 2.20%

ABCM 0.04%

ABEO -2.14%

ABIO -3.73%

ABOS 0.70%

ABSI 2.04%

ABUS -1.96%

ABVX -1.50%

ACAD -0.58%

ACER -17.95%

ACET -4.76%

ACGN 1.29%

ACHL -4.11%

ACHV -0.22%

ACIU -0.75%

ACLX 0.95%

ACRV -2.31%

ACST -2.90%

ACXP 1.38%

ADAG 4.64%

ADAP -4.11%

ADGI 0.87%

ADIL 1.75%

ADMA -2.13%

ADPT 0.15%

ADTX -2.08%

ADVM -3.33%

ADXN -1.60%

AEON -4.50%

AEZS -2.49%

AFMD -1.60%

AGEN -2.02%

AGIO -2.25%

AGLE 6.66%

AGTC 0.00%

AIKI 0.85%

AIMDW -13.88%

AKBA 0.40%

AKRO -3.15%

AKTX 1.05%

AKUS 0.00%

ALBO 0.00%

ALDX -2.10%

ALEC 0.80%

ALGS -0.74%

ALKS 0.48%

ALLK -9.75%

ALLO -5.86%

ALLR -0.82%

ALNA 3.16%

ALNY 2.49%

ALPN 0.02%

ALPX 0.00%

ALRN -1.33%

ALT -9.24%

ALVR 2.98%

ALXN 0.00%

ALXO -13.09%

ALZN 5.27%

AMRN 0.19%

AMTI -3.13%

ANAB 1.22%

ANEB -1.52%

ANGN 0.00%

ANIX -1.62%

ANL -6.60%

ANNX -0.22%

ANPC -3.15%

APGE -0.37%

APGN 8.48%

APGNW 30.65%

APLM -2.32%

APLS 0.22%

APLT -3.15%

APM 0.36%

APOP 0.38%

APRE 0.60%

APTO 5.98%

APTX 3.17%

APVO 0.93%

ARAV -13.39%

ARCT -5.02%

ARDS -14.23%

ARDX 0.25%

ARGX -0.90%

ARNA 0.00%

ARPO -0.90%

ARQT -0.21%

ARTL -2.50%

ARTLW 0.00%

ARVN 5.61%

ARWR -1.12%

ASLN -3.88%

ASMB -5.81%

ASND -1.55%

ATAI -1.85%

ATHA 5.01%

ATHE 0.56%

ATHX -33.50%

ATNF 4.32%

ATOS 1.93%

ATRA -1.93%

ATXI -2.78%

ATXS -0.11%

AUPH -0.90%

AURA 2.79%

AUTL -1.29%

AVBP -3.32%

AVEO 0.00%

AVIR -0.44%

AVRO -1.41%

AVTE -3.79%

AVTX -1.25%

AVXL -3.70%

AXLA 0.00%

AXSM -1.08%

AYLA 0.00%

AZRX 2.07%

BBI 2.17%

BBIO 3.61%

BCAB 5.56%

BCDA -2.23%

BCDAW -41.77%

BCEL 0.00%

BCLI 2.83%

BCRX 0.33%

BCTX 8.90%

BCTXW -16.32%

BCYC 1.15%

BDRX -4.64%

BDTX -1.73%

BEAM 1.20%

BFRA -2.91%

BGNE -2.78%

BIOR -6.15%

BIVI 3.41%

BLCM -6.68%

BLI -5.88%

BLPH 0.00%

BLRX -0.89%

BLTE -0.78%

BLU 0.03%

BLUE 0.58%

BMEA -10.71%

BMRN 0.15%

BNOX 6.22%

BNTC -0.42%

BNTX -1.62%

BOLD -12.19%

BOLT -0.05%

BPMC -0.85%

BPTH 0.00%

BPTS -13.47%

BRNS 0.00%

BRTX -3.52%

BTAI 25.47%

BTTX 50.67%

BTX 0.05%

BVXV 0.74%

BXRX 7.39%

BYSI 4.24%

CABA 1.87%

CADL -1.95%

CALA 0.00%

CALC -1.77%

CALT -1.59%

CAPR -1.72%

CARA -0.06%

CARM 13.48%

CASI -1.65%

CATB -6.97%

CBAY 0.03%

CBIO -2.65%

CBLI -7.31%

CBUS -5.67%

CCCC -5.52%

CCXI 0.00%

CDAK 0.00%

CDIO -2.18%

CDIOW 24.00%

CDMO -2.82%

CDMOP 0.04%

CDT -6.50%

CDTTW -39.60%

CDTX -1.31%

CDXC 0.20%

CDXS 7.23%

CELC -3.94%

CELU -1.00%

CELUW 11.80%

CERC -1.68%

CERE -1.42%

CERO -3.88%

CEROW -21.56%

CFRX -27.95%

CGEM -3.10%

CGEN -3.31%

CGON -1.69%

CGTX -3.98%

CHMA -6.00%

CHRS 1.90%

CINC 0.00%

CING -2.67%

CINGW 34.95%

CKPT -3.81%

CLBS -16.75%

CLDX -1.02%

CLGN 0.34%

CLLS -4.15%

CLNN 0.00%

CLNNW 0.00%

CLRB 6.30%

CLSD 0.00%

CLSN -0.68%

CLVS 0.00%

CMMB -0.98%

CMND 3.55%

CMPI 0.00%

CMPX -1.42%

CMRA 0.00%

CMRAW 33.33%

CMRX -3.47%

CNCE 0.00%

CNSP -36.62%

CNST 0.00%

CNTA -0.28%

CNTB 0.00%

CNTX -7.31%

COCP -2.00%

COEPW 32.45%

COGT -3.13%

CORT 2.90%

COYA -1.46%

CPRX -1.02%

CRBP -3.13%

CRBU -5.97%

CRDF -0.89%

CRGX -0.07%

CRIS -1.72%

CRNX -5.75%

CRSP 0.69%

CRTX 2.63%

CRVO -5.75%

CRVS 1.69%

CSBR -1.59%

CTCX -1.60%

CTIC 0.06%

CTMX -3.73%

CTNM -2.11%

CTXR 2.44%

CUE 6.57%

CVAC -5.23%

CVKD -2.85%

CWBR 2.80%

CYAD -12.96%

CYCC 9.09%

CYCCP 5.49%

CYCN -0.24%

CYT -2.27%

CYTK -2.17%

CYTO -1.82%

DARE 4.02%

DAWN -1.12%

DBTX -0.81%

DBVT 4.17%

DFFN 10.28%

DICE 0.06%

DMAC 28.38%

DNLI -1.47%

DNTH -10.35%

DOMH 2.43%

DRMA -1.68%

DRMAW -1.25%

DRNA 0.00%

DRTS 3.45%

DRTSW 0.00%

DRUG 0.95%

DSGN -2.72%

DTIL 1.99%

DYAI 12.26%

EARS -1.77%

EDIT -2.31%

EDSA 3.19%

EFTR 5.89%

EFTRW -51.85%

EIGR -9.21%

ELAB -2.84%

ELDN 8.99%

ELEV -5.60%

ELOX -5.38%

ELTX -4.26%

ELVN -3.92%

ELYM 2.23%

ENGN -1.72%

ENGNW 0.00%

ENLV 2.90%

ENOB 1.79%

ENSC 3.23%

ENTA 0.08%

ENTO -2.42%

ENTX 1.60%

ENVB 1.58%

EPIX -2.36%

EPRX -1.15%

EPZM 0.00%

EQ 0.34%

EQRX -2.09%

EQRXW 0.00%

ERAS -0.72%

ERNA 0.00%

ERYP 1.30%

ESLA 4.30%

ESLAW 16.64%

ETNB -3.05%

ETON 1.82%

ETTX 0.00%

EVAX -2.14%

EVGN 4.76%

EVLO 0.00%

EWTX -0.17%

EXAI -1.32%

EXEL 0.11%

EYEG -0.69%

EYEN 1.42%

EYPT 0.61%

FATE -9.81%

FBIO 0.85%

FBIOP -0.37%

FBLG -14.69%

FBRX -0.02%

FDMT -3.39%

FENC -1.05%

FGEN -7.27%

FHTX 6.87%

FIXX 0.77%

FMTX 0.00%

FNCH 8.87%

FOLD -1.88%

FREQ 4.76%

FRLN 0.15%

FRTX 0.00%

FSTX 0.00%

FTRE -0.36%

FULC -3.43%

FUSN 0.00%

FWBI 4.59%

FWP 0.00%

GALT -6.28%

GANX -2.31%

GBIO -2.83%

GBT 0.01%

GDTC 0.50%

GERN -4.54%

GHRS -2.30%

GLMD -4.13%

GLPG -2.15%

GLSI 1.43%

GLTO -2.16%

GLUE -3.14%

GLYC -9.67%

GMAB -0.23%

GMDA -18.25%

GMTX 0.00%

GNCA -85.71%

GNFT -3.14%

GNLX 0.44%

GNPX 0.00%

GNTA 3.94%

GOSS -10.61%

GOVX 0.91%

GOVXW -49.04%

GPCR -8.66%

GRAY -10.80%

GRCL 0.05%

GRNA -0.03%

GRNAW 8.91%

GRPH -2.75%

GRTS 1.18%

GRTX 5.14%

GTHX 0.23%

GUTS -5.08%

GXGXW 41.67%

GYRE -8.79%

HALO -1.07%

HARP 0.09%

HCWB -3.75%

HEPA -4.09%

HGEN -84.62%

HILS 5.66%

HLVX 0.15%

HOOK 2.33%

HOTH -3.51%

HOWL -1.71%

HRMY 2.03%

HRTX 4.11%

HSTO 0.00%

HUMA 0.81%

HUMAW -0.01%

IBRX -4.13%

ICCC 0.22%

ICPT 0.21%

ICU 19.34%

ICUCW 20.46%

ICVX -0.91%

IDRA -23.04%

IDYA -1.54%

IFRX -1.54%

IGMS -0.29%

IKNA 0.89%

IKT 0.70%

IMAB 2.03%

IMCR -2.95%

IMGN 0.02%

IMGO 0.00%

IMMP 4.74%

IMMX -7.76%

IMNM 0.87%

IMNN 0.88%

IMPL -27.27%

IMRA 15.96%

IMRN -1.18%

IMRX 0.00%

IMTX -0.75%

IMTXW 6.00%

IMUX 1.85%

IMV 0.00%

IMVT -4.78%

INAB -0.56%

INBX 0.76%

INCY -1.25%

INDP 11.07%

INFI -52.38%

INKT -0.01%

INM 3.14%

INMB 1.68%

INO -1.30%

INSM -1.26%

INTS -2.75%

INVA 0.53%

INZY 0.69%

IOBT -10.67%

IONS 0.68%

IOVA -2.78%

IPA -0.49%

IPHA 5.58%

IPSC -2.54%

IRON -1.79%

ISEE 0.38%

ITOS -1.71%

ITRM 1.67%

IVA 6.96%

IVVD -3.29%

JAGX 0.79%

JANX -3.81%

JAZZ -0.51%

JNCE 0.00%

JSPR -6.17%

JSPRW 20.88%

JUNS 0.00%

JUNSW 0.00%

KA -3.54%

KALV -4.68%

KDNY 0.22%

KMPH -0.34%

KNSA -2.06%

KNTE -0.38%

KOD -6.13%

KPRX 0.96%

KPTI -5.05%

KRBP -10.00%

KRON 0.58%

KROS -1.10%

KRRO -8.11%

KRTX 0.03%

KRYS -0.55%

KTRA 9.14%

KTTA -6.79%

KTTAW 0.92%

KURA -0.29%

KYMR -2.76%

KYTX -4.52%

KZIA 2.65%

KZR -0.85%

LABP 0.57%

LBPH -1.18%

LBPS 0.00%

LBPSW 14.81%

LEGN 1.82%

LENZ -4.30%

LEXX 0.81%

LEXXW -14.63%

LGND -0.50%

LGNDV 0.00%

LGVN -7.71%

LIAN -8.28%

LIFE 2.70%

LIPO -3.87%

LIXT -5.24%

LIXTW 63.57%

LJPC -0.32%

LMNL 0.12%

LOGC 1.39%

LPCN -1.86%

LPTX -2.72%

LQDA -0.16%

LRMR -1.56%

LSTA -4.06%

LTRN 1.37%

LUMO -1.32%

LVTX -1.03%

LXEO -2.79%

LXRX -1.77%

LYEL -36.03%

LYRA 1.20%

MACK 0.10%

MBIO -10.02%

MBRX -1.72%

MCRB 2.89%

MDGL -0.89%

MDNA -13.16%

MDWD -0.14%

MDXG -2.80%

MEIP 1.40%

MESO -1.41%

MGNX -2.34%

MGTA -7.74%

MGTX -3.57%

MGX -4.01%

MIRM -1.02%

MIRO 0.59%

MIST 1.15%

MITO 0.00%

MLEC -7.69%

MLECW 2.31%

MLND -5.36%

MLTX 0.56%

MLYS -7.12%

MNKD 0.48%

MNMD -0.07%

MNOV 2.11%

MNPR -8.52%

MOLN 1.79%

MOR 1.20%

MORF -3.40%

MREO -2.57%

MRKR 2.57%

MRNA -5.87%

MRNS -4.04%

MRSN -2.14%

MRTX -0.17%

MRUS 0.29%

MRVI -1.16%

MTCR -1.29%

MTEM 4.46%

MTP -18.50%

MURA -0.93%

MYMD 5.46%

NAMS 3.33%

NAMSW -0.21%

NAUT 1.55%

NBRV 0.71%

NBSE -1.56%

NBTX 12.09%

NCNA 0.73%

NERV -0.63%

NEXI 4.04%

NGM -1.28%

NGNE -1.42%

NKGN 10.08%

NKGNW 8.00%

NKTR -4.21%

NKTX -5.06%

NLSP 5.91%

NLSPW 26.67%

NMRA -3.43%

NMTR -42.97%

NOVN -24.84%

NRBO 10.40%

NRIX -2.12%

NRSN -5.12%

NRSNW 0.00%

NRXP -3.72%

NRXPW 18.33%

NRXS 4.82%

NTBL 3.42%

NTEC -12.45%

NTHI 0.00%

NTLA -6.83%

NTRBW -31.07%

NUVL -1.61%

NVAX -2.28%

NVCT 3.55%

NVIV -34.28%

NXTC -2.94%

NYMX -0.05%

OABI 1.45%

OABIW -10.06%

OBIO -3.07%

OBSV 0.00%

OCEA 0.00%

OCGN 2.54%

OCS -1.00%

OCUL -0.08%

OCUP 1.84%

ODT -4.27%

OKYO 1.51%

OLMA -5.03%

OMER -1.03%

OMGA 5.64%

ONCO 4.54%

ONCR -3.08%

ONCS 31.87%

ONCT -3.05%

ONCY 1.49%

ONTX -0.47%

ONVO 0.47%

OPNT 0.00%

OPT 3.09%

ORGS 0.96%

ORIC -3.56%

ORMP 18.22%

ORPH 0.00%

ORTX 0.30%

OSMT -1.77%

OTIC -92.64%

OTLK -2.22%

OVID 0.52%

OYST 0.00%

PALI 1.30%

PASG -1.30%

PBLA -7.50%

PBM -3.48%

PBYI 1.59%

PCSA 0.00%

PCVX -0.21%

PDSB -4.43%

PEPG 0.78%

PGEN -2.99%

PHAR 1.51%

PHAS 0.00%

PHAT -1.06%

PHIO -3.47%

PHIOW 36.47%

PHVS -7.32%

PHXM -5.20%

PIRS 0.58%

PKBO 0.00%

PKBOW 999 900.00%

PLRX -1.33%

PLUR 7.39%

PMN 0.72%

PMVP -0.30%

PNT 0.16%

PPBT -5.61%

PRAX 3.06%

PRDS 0.93%

PRLD -2.37%

PROG -3.47%

PROK 0.37%

PRQR -0.66%

PRTA -2.45%

PRTC 0.49%

PRTG 7.02%

PRTK 1.83%

PRVB 0.00%

PSTI -2.91%

PSTV -10.46%

PSTX -1.36%

PTCT -0.26%

PTE -0.82%

PTGX -0.87%

PTIXW -48.41%

PULM 2.60%

PXMD 4.76%

PYPD 0.07%

PYXS 1.14%

QLGN -3.00%

QNCX 5.70%

QNRX -1.14%

QSI -11.54%

QSIAW -3.13%

QTTB -3.45%

QURE -0.78%

RAIN -1.63%

RANI 6.42%

RAPT -1.30%

RARE 1.39%

RCKT -8.47%

REGN 0.20%

RENB -3.42%

REPL -2.15%

RETA 0.02%

REUN -0.89%

REVB -2.79%

REVBU 3.46%

REVBW 4.38%

RGLS -6.78%

RGNX -5.56%

RIGL -3.28%

RLAY -3.56%

RLMD 0.35%

RLYB -1.34%

RNA 0.92%

RNAC -2.94%

RNAZ -1.90%

RNXT 0.89%

ROIV -2.08%

ROIVW 4.56%

RPHM 0.00%

RPRX 0.30%

RPTX 0.15%

RUBY 2.70%

RVLP -32.05%

RVMD -0.87%

RVMDW -30.00%

RVNC 0.21%

RVPH -0.79%

RVPHW 1.62%

RXDX 0.09%

RXRX -4.69%

RYTM -5.61%

RYZB 0.02%

RZLT 2.55%

SABS -1.37%

SABSW -11.81%

SAGE 1.47%

SANA -3.41%

SAVA -0.16%

SAVAW 0.00%

SBBP 1.52%

SBTX 1.03%

SCNI -0.06%

SCPH 5.30%

SCPS 0.00%

SEEL -4.12%

SEER 0.29%

SELB -8.00%

SESN 7.29%

SGEN -0.07%

SGMO -1.39%

SGMT -2.18%

SGTX -2.56%

SIOX 22.63%

SLDB -8.97%

SLGL 4.12%

SLN -4.57%

SLNO -4.58%

SLRX 5.26%

SLS -1.71%

SMMT -1.62%

SNDX 1.33%

SNGX -4.91%

SNPX -4.44%

SONN 0.00%

SPPI -0.49%

SPRB 0.63%

SPRC -2.75%

SPRO 0.05%

SRNE -34.00%

SRPT -0.91%

SRRA 0.00%

SRRK -2.23%

SRZN -2.45%

STAB 0.00%

STOK -5.52%

STRO -3.52%

STSA 0.00%

STTK -1.69%

SURF -0.93%

SVRA -6.71%

SWTX -0.38%

SYBX -1.29%

SYRS -1.55%

TALS -0.73%

TARA -7.62%

TARS 0.45%

TBPH 0.48%

TCBP 2.48%

TCDA 0.00%

TCON 2.46%

TCRR 0.00%

TCRT 0.08%

TCRX -1.05%

TECH -0.22%

TENX 1.91%

TERN -8.28%

TFFP -5.33%

TGTX -4.33%

THRX 0.12%

TIL -1.09%

TLC 0.00%

TLSA -4.60%

TNGX -3.35%

TNXP -6.00%

TNYA -4.73%

TPST 5.27%

TRDA -4.06%

TRVI 2.30%

TRVN 1.60%

TSHA -22.27%

TSVT -3.46%

TTNP -7.66%

TVTX 1.26%

TYRA -8.54%

UBX -2.48%

UNCY -4.00%

URGN -1.15%

UTHR 0.61%

VACC 11.36%

VALN -4.07%

VAXX 100.00%

VBIV 0.33%

VBLT -8.77%

VCEL 0.96%

VCNX 10.35%

VCYT -1.34%

VERA -3.92%

VERU 0.97%

VERV -2.87%

VIGL 4.84%

VINC 2.28%

VIR 0.98%

VIRI -1.85%

VIRX 3.15%

VKTX -1.26%

VLON -13.04%

VNDA -3.50%

VOR -1.62%

VRCA 0.00%

VRDN -4.35%

VRNA -0.53%

VRPX 0.38%

VRTX 0.32%

VSTM -0.85%

VTGN -0.45%

VTVT -2.97%

VTYX -1.05%

VXRT -4.34%

VYGR 0.00%

VYNE -4.62%

VYNT 7.78%

WINT 2.18%

WVE -6.08%

XBIO 1.03%

XBIT 0.87%

XCUR 3.55%

XENE -1.35%

XERS 2.62%

XFOR 5.02%

XLO 3.94%

XLRN 0.00%

XNCR 0.62%

XOMA -3.34%

XOMAO -0.16%

XOMAP -0.82%

XRTX -8.00%

YMAB -1.59%

ZGNX 0.00%

ZIOP -0.88%

ZLAB -2.67%

ZNTL -2.38%

ZSAN 0.00%

Insider Trading

Date	Person	Action	Amount	type
2024-06-21	Dunlop A. Sinclair	Sell	35 305	Common Stock
2024-06-21	Dunlop A. Sinclair	Sell	1 695	Common Stock
2024-05-20	Deschatelets Pascal	Buy	24 500	Common Stock
2024-05-20	Deschatelets Pascal	Sell	24 500	Stock Option (Right to Buy)
2024-05-08	Deschatelets Pascal	Buy	78 907	Common Stock

INSIDER POWER
-16.70
Last 100 transactions
Buy: 863 969 \| Sell: 1 167 718

相关性 (AI algo v.1.1b): Overvalued: -0.20% $40.57 paired level. (算法实时跟踪最相关股票的变化并提供即时更新)

音量相关性

長: 0.88 (strong)

短: -0.93 (very strong negative)

Signal:(39) Neutral

Apellis Pharmaceuticals 相关性

10 最正相关
OZEM	1
DLHC	0.954
MPAA	0.943
APDN	0.942
MBIO	0.935
JACK	0.933
ALGT	0.933
SHLS	0.932
TOI	0.931
APVO	0.929

10 最负相关
VCTR	-0.945
BNTC	-0.941
AEYE	-0.94
NKTR	-0.939
SMTC	-0.938
KALU	-0.935
FRLA	-0.931
RVMD	-0.929
CGBD	-0.928
GGAL	-0.928

你知道吗？

相关性是描述两个变量之间关系的统计指标。它的取值范围为-1到1，其中-1表示完全负相关（一个变量增加，另一个变量减少），1表示完全正相关（一个变量增加，另一个变量也增加），0表示没有相关性（变量之间没有关系）。

相关性可用于分析任何两个变量之间的关系，而不仅仅是股票。它通常用于金融、经济学、心理学等领域。

Apellis Pharmaceuticals 相关性 - 货币/商品

0.58
( weak )

0.05
( neutral )

0.00
( neutral )

0.40
( neutral )

0.00
( neutral )

-0.79
( moderate negative )

Apellis Pharmaceuticals 财务报表

Annual	2023
营收:	$396.59M
毛利润:	$336.38M (84.82 %)
EPS:	$-4.45

FY	2023
营收:	$396.59M
毛利润:	$336.38M (84.82 %)
EPS:	$-4.45

FY	2022
营收:	$75.42M
毛利润:	$69.79M (92.53 %)
EPS:	$-6.15

FY	2021
营收:	$66.56M
毛利润:	$61.36M (92.19 %)
EPS:	$-8.84

Financial Reports:

No articles found.

Apellis Pharmaceuticals Options Data

Calls

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Puts

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Apellis Pharmaceuticals

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. The company's lead product candidate is pegcetacoplan that is in Phase III clinical trials for the treatment of geographic atrophy (GA) in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria (PNH) diseases. It also develops EMPAVELI (systemic pegcetacoplan) for the treatment of cold agglutinin disease (CAD), and hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) in hematology; C3 glomerulopathy (C3G), and immune complex membranoproliferative glomerulonephritis (IC-MPGN) in nephrology; and amyotrophic lateral sclerosis (ALS) in neurology. In addition, the company develops APL-2006, a bispecific C3 and VEGF inhibitor for treating complement-mediated disorders; APL-1030, a C3 inhibitor for the treatment of multiple neurodegenerative diseases; and the combination of EMPAVELI and a small interfering RNA, or siRNA for reducing the production of C3 proteins by the liver. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) to co-develop pegcetacoplan; and a research collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. Apellis Pharmaceuticals, Inc. was incorporated in 2009 and is based in Waltham, Massachusetts.