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Commentary (23 saus. 2024 @ 23:00):

Orchard Therapeutics plc, a biopharmaceutical company, develops gene therapies for serious and life-threatening rare diseases in the United Kingdom, European Union, and the United States...

Stats
Dzisiejszy wolumen	372 349
Średni wolumen	105 224
Kapitalizacja rynkowa	380.11M
EPS	$-1.550 ( Q3 \| 2023-11-13 )
Następna data zysków	( $0 ) 2024-08-03
Last Dividend	$0 ( N/A )
Next Dividend	$0 ( N/A )
P/E	-4.07 (Sector) 42.63 (Industry) 24.32
ATR14	$0.0590 (0.35%)

AADI 3.55%

ABCL -3.79%

ABCM 0.04%

ABEO -5.02%

ABIO -0.29%

ABOS -3.03%

ABSI 0.66%

ABUS 0.66%

ABVX 2.61%

ACAD 3.79%

ACER -17.95%

ACET 9.49%

ACGN 1.29%

ACHL 0.22%

ACHV -4.83%

ACIU 2.47%

ACLX -0.09%

ACRV -5.30%

ACST -0.31%

ACXP -2.15%

ADAG 0.69%

ADAP -1.06%

ADGI 0.87%

ADIL 2.68%

ADMA 0.09%

ADPT 1.54%

ADTX -2.08%

ADVM 1.63%

ADXN -5.75%

AEON -7.34%

AEZS -1.10%

AFMD 1.02%

AGEN 4.60%

AGIO 0.02%

AGLE 6.66%

AGTC 0.00%

AIKI 0.85%

AIMDW -13.88%

AKBA -0.69%

AKRO 2.80%

AKTX -1.08%

AKUS 0.00%

ALBO 0.00%

ALDX -5.46%

ALEC 0.44%

ALGS -4.88%

ALKS -1.28%

ALLK 8.11%

ALLO 2.35%

ALLR -28.40%

ALNA 3.16%

ALNY 34.52%

ALPN 0.02%

ALPX 0.00%

ALRN -1.60%

ALT 11.39%

ALVR 4.92%

ALXN 0.00%

ALXO -0.15%

ALZN -7.26%

AMRN 2.72%

AMTI -3.13%

ANAB 0.21%

ANEB -1.49%

ANGN 0.00%

ANIX -0.79%

ANL 0.29%

ANNX -4.22%

ANPC -3.15%

APGE 2.63%

APGN 8.48%

APGNW 30.65%

APLM 9.95%

APLS 0.92%

APLT 1.76%

APM 1.73%

APOP 0.38%

APRE 3.24%

APTO -2.37%

APTX 3.17%

APVO 1.15%

ARAV -13.39%

ARCT -0.44%

ARDS 2.49%

ARDX 1.46%

ARGX 11.69%

ARNA 0.00%

ARPO -0.90%

ARQT 4.59%

ARTL -2.71%

ARTLW 0.00%

ARVN -0.99%

ARWR 6.82%

ASLN -2.99%

ASMB 0.38%

ASND 1.20%

ATAI 4.48%

ATHA 1.28%

ATHE 2.27%

ATHX -33.50%

ATNF 2.05%

ATOS -5.31%

ATRA 0.67%

ATXI 9.52%

ATXS -2.65%

AUPH 2.35%

AURA -1.25%

AUTL -2.87%

AVBP -0.78%

AVEO 0.00%

AVIR 1.45%

AVRO -1.41%

AVTE -3.85%

AVTX 2.99%

AVXL 3.19%

AXLA 0.00%

AXSM 2.76%

AYLA 0.00%

AZRX 2.07%

BBI 2.17%

BBIO -15.94%

BCAB 3.31%

BCDA -5.67%

BCDAW -39.75%

BCEL 0.00%

BCLI 2.70%

BCRX -2.34%

BCTX -7.44%

BCTXW -18.26%

BCYC 0.10%

BDRX -15.63%

BDTX 0.83%

BEAM 8.24%

BFRA -2.91%

BGNE 1.95%

BIOR 1.50%

BIVI 0.96%

BLCM -6.68%

BLI -5.88%

BLPH 0.00%

BLRX 3.39%

BLTE 0.27%

BLU 0.03%

BLUE 13.45%

BMEA 5.51%

BMRN 1.62%

BNOX 2.99%

BNTC 4.80%

BNTX 2.33%

BOLD 13.42%

BOLT -1.45%

BPMC 1.79%

BPTH 0.88%

BPTS -13.47%

BRNS 0.00%

BRTX 1.72%

BTAI 4.39%

BTTX 0.00%

BTX 0.05%

BVXV 0.74%

BXRX 7.39%

BYSI -1.78%

CABA -1.53%

CADL 1.82%

CALA 0.00%

CALC -1.87%

CALT 1.83%

CAPR 1.91%

CARA 22.71%

CARM 9.80%

CASI 7.65%

CATB -6.97%

CBAY 0.03%

CBIO -2.65%

CBLI -7.31%

CBUS -4.40%

CCCC 11.08%

CCXI 0.00%

CDAK 0.00%

CDIO -0.17%

CDIOW 36.86%

CDMO -4.38%

CDMOP 0.04%

CDT -7.05%

CDTTW -23.91%

CDTX -2.84%

CDXC -6.59%

CDXS 2.04%

CELC 4.58%

CELU 0.66%

CELUW 11.18%

CERC -1.68%

CERE -0.55%

CERO 2.09%

CEROW -22.90%

CFRX -27.95%

CGEM -0.34%

CGEN -5.08%

CGON 1.50%

CGTX -2.63%

CHMA -6.00%

CHRS -2.40%

CINC 0.00%

CING 4.73%

CINGW 73.79%

CKPT 15.56%

CLBS -16.75%

CLDX 2.55%

CLGN 6.22%

CLLS 1.06%

CLNN -3.46%

CLNNW -33.25%

CLRB 0.00%

CLSD 0.00%

CLSN -0.68%

CLVS 0.00%

CMMB 8.57%

CMND -7.59%

CMPI 0.00%

CMPX 0.91%

CMRA 0.00%

CMRAW 33.33%

CMRX 1.85%

CNCE 0.00%

CNSP 12.63%

CNST 0.00%

CNTA -2.31%

CNTB -6.25%

CNTX 0.93%

COCP -1.88%

COEPW 0.00%

COGT 1.14%

CORT 1.83%

COYA -2.48%

CPRX -1.28%

CRBP 2.42%

CRBU 8.72%

CRDF -3.67%

CRGX 4.50%

CRIS 3.02%

CRNX 0.18%

CRSP 3.02%

CRTX 2.63%

CRVO 0.40%

CRVS 2.81%

CSBR -1.20%

CTCX -7.84%

CTIC 0.06%

CTMX 3.10%

CTNM 3.23%

CTXR 4.68%

CUE 8.89%

CVAC 6.44%

CVKD 6.24%

CWBR 0.00%

CYAD -12.96%

CYCC -5.01%

CYCCP 4.03%

CYCN 6.69%

CYT -2.27%

CYTK 0.71%

CYTO 2.61%

DARE 1.96%

DAWN -1.10%

DBTX -0.81%

DBVT -1.80%

DFFN 10.28%

DICE 0.06%

DMAC 2.78%

DNLI 1.24%

DNTH -0.04%

DOMH -2.63%

DRMA 12.50%

DRMAW -1.25%

DRNA 0.00%

DRTS 1.62%

DRTSW 0.00%

DRUG -3.77%

DSGN -0.59%

DTIL 0.85%

DYAI -9.66%

EARS -1.77%

EDIT -0.59%

EDSA -0.11%

EFTR -75.81%

EFTRW -96.33%

EIGR -9.21%

ELAB 0.86%

ELDN -4.40%

ELEV -4.30%

ELOX 0.00%

ELTX 6.89%

ELVN 1.87%

ELYM -8.69%

ENGN -9.67%

ENGNW -7.87%

ENLV 3.68%

ENOB 1.79%

ENSC 4.98%

ENTA 2.43%

ENTO -2.13%

ENTX 1.98%

ENVB 9.19%

EPIX -1.02%

EPRX 0.57%

EPZM 0.00%

EQ 2.52%

EQRX -2.09%

EQRXW 0.00%

ERAS 2.37%

ERNA -4.64%

ERYP 1.30%

ESLA -0.50%

ESLAW 0.00%

ETNB -0.82%

ETON -0.60%

ETTX 0.00%

EVAX -5.28%

EVGN -2.18%

EVLO 0.00%

EWTX -1.99%

EXAI -2.78%

EXEL 0.54%

EYEG 0.11%

EYEN 2.28%

EYPT 0.59%

FATE 2.13%

FBIO -3.95%

FBIOP 0.59%

FBLG 5.49%

FBRX 0.27%

FDMT 1.35%

FENC -1.09%

FGEN 6.19%

FHTX 0.38%

FIXX 0.77%

FMTX 0.00%

FNCH -6.77%

FOLD -0.89%

FREQ 4.76%

FRLN 0.15%

FRTX -4.51%

FSTX 0.00%

FTRE -0.65%

FULC -5.09%

FUSN 0.00%

FWBI 4.59%

FWP 0.00%

GALT -8.97%

GANX 0.00%

GBIO 1.45%

GBT 0.01%

GDTC 5.61%

GERN -1.29%

GHRS 0.42%

GLMD -1.83%

GLPG 1.67%

GLSI -4.73%

GLTO 5.51%

GLUE 4.96%

GLYC 3.61%

GMAB -0.81%

GMDA -18.25%

GMTX 0.00%

GNCA -85.71%

GNFT 1.29%

GNLX 10.68%

GNPX 0.00%

GNTA 7.74%

GOSS 27.09%

GOVX 30.04%

GOVXW 49.24%

GPCR -4.15%

GRAY -10.80%

GRCL 0.05%

GRNA -0.03%

GRNAW 8.91%

GRPH -2.75%

GRTS 4.76%

GRTX 40.48%

GTHX -10.48%

GUTS 5.77%

GXGXW 41.67%

GYRE -3.28%

HALO 0.99%

HARP 0.09%

HCWB 10.69%

HEPA 5.42%

HGEN -84.62%

HILS 5.66%

HLVX 2.75%

HOOK -1.07%

HOTH 0.67%

HOWL -9.38%

HRMY -0.10%

HRTX -1.55%

HSTO 0.00%

HUMA -1.35%

HUMAW 5.19%

IBRX 1.10%

ICCC -0.22%

ICPT 0.21%

ICU 10.12%

ICUCW 14.68%

ICVX -0.91%

IDRA -23.04%

IDYA 0.03%

IFRX 8.44%

IGMS 0.00%

IKNA -2.33%

IKT -5.00%

IMAB 2.38%

IMCR -0.28%

IMGN 0.02%

IMGO 0.00%

IMMP -2.92%

IMMX 11.76%

IMNM -4.02%

IMNN -4.46%

IMPL -27.27%

IMRA 15.96%

IMRN 12.11%

IMRX 4.20%

IMTX -1.37%

IMTXW -14.50%

IMUX -0.90%

IMV 0.00%

IMVT 0.18%

INAB -0.84%

INBX 2.18%

INCY 0.84%

INDP -1.33%

INFI -52.38%

INKT -1.62%

INM 9.72%

INMB 1.62%

INO -1.61%

INSM 0.65%

INTS 4.74%

INVA 0.63%

INZY 0.67%

IOBT 0.00%

IONS 6.81%

IOVA 1.87%

IPA -1.92%

IPHA -5.16%

IPSC -6.29%

IRON 1.81%

ISEE 0.38%

ITOS 0.61%

ITRM -5.65%

IVA -0.71%

IVVD 2.42%

JAGX -3.32%

JANX 5.52%

JAZZ 1.72%

JNCE 0.00%

JSPR 1.72%

JSPRW 4.71%

JUNS 0.00%

JUNSW 0.00%

KA 13.13%

KALV -0.17%

KDNY 0.22%

KMPH -0.34%

KNSA 1.40%

KNTE -0.38%

KOD 3.41%

KPRX 9.68%

KPTI 12.76%

KRBP -0.40%

KRON -6.48%

KROS 0.09%

KRRO -0.76%

KRTX 0.03%

KRYS 1.97%

KTRA 6.15%

KTTA 4.85%

KTTAW -5.17%

KURA 0.67%

KYMR -1.69%

KYTX 2.07%

KZIA -15.51%

KZR 1.12%

LABP 0.57%

LBPH 0.05%

LBPS 0.00%

LBPSW 14.81%

LEGN 1.13%

LENZ -1.52%

LEXX -1.49%

LEXXW -0.19%

LGND 0.72%

LGNDV 0.00%

LGVN -12.73%

LIAN -8.28%

LIFE 2.70%

LIPO 10.88%

LIXT -1.57%

LIXTW 0.00%

LJPC -0.32%

LMNL 0.12%

LOGC 1.27%

LPCN 3.56%

LPTX -2.08%

LQDA 3.28%

LRMR -10.33%

LSTA -3.26%

LTRN -5.78%

LUMO 1.79%

LVTX 0.27%

LXEO 4.94%

LXRX -2.16%

LYEL 3.41%

LYRA -2.78%

MACK 0.10%

MBIO 2.70%

MBRX -3.48%

MCRB -2.19%

MDGL 2.00%

MDNA -13.16%

MDWD 7.88%

MDXG -1.02%

MEIP -2.80%

MESO -3.28%

MGNX 2.97%

MGTA -7.74%

MGTX -3.18%

MGX 0.56%

MIRM 8.74%

MIRO 0.59%

MIST 0.72%

MITO 0.00%

MLEC -5.36%

MLECW 90.24%

MLND -5.36%

MLTX 0.73%

MLYS 4.90%

MNKD 6.26%

MNMD 0.27%

MNOV 0.00%

MNPR 15.76%

MOLN -25.10%

MOR -0.11%

MORF 10.26%

MREO -5.53%

MRKR 9.03%

MRNA 2.70%

MRNS 3.01%

MRSN 3.76%

MRTX -0.17%

MRUS 3.77%

MRVI -2.35%

MTCR -1.29%

MTEM -4.59%

MTP -18.50%

MURA -0.62%

MYMD -4.12%

NAMS 8.93%

NAMSW 26.87%

NAUT -8.57%

NBRV 0.71%

NBSE -1.56%

NBTX 4.81%

NCNA -0.34%

NERV -5.52%

NEXI -2.44%

NGM -1.28%

NGNE 2.39%

NKGN 0.00%

NKGNW 8.00%

NKTR 0.86%

NKTX 1.82%

NLSP -5.16%

NLSPW 28.30%

NMRA 0.00%

NMTR -42.97%

NOVN -24.84%

NRBO 0.49%

NRIX -1.27%

NRSN -3.99%

NRSNW 0.00%

NRXP 0.75%

NRXPW 0.00%

NRXS -0.78%

NTBL 0.36%

NTEC -12.45%

NTHI 0.00%

NTLA 3.22%

NTRBW 0.00%

NUVL 1.72%

NVAX 0.14%

NVCT 2.13%

NVIV -34.28%

NXTC 3.70%

NYMX -0.05%

OABI 1.75%

OABIW -3.65%

OBIO 9.02%

OBSV 0.00%

OCEA 7.75%

OCGN -5.26%

OCS 1.37%

OCUL 4.48%

OCUP 1.27%

ODT -4.27%

OKYO -1.63%

OLMA 2.15%

OMER 2.90%

OMGA -0.41%

ONCO -6.85%

ONCR -3.08%

ONCS 31.87%

ONCT -1.85%

ONCY 0.00%

ONTX -0.47%

ONVO -2.28%

OPNT 0.00%

OPT -4.93%

ORGS -3.25%

ORIC -1.11%

ORMP -3.04%

ORPH 0.00%

ORTX 0.30%

OSMT -1.77%

OTIC -92.64%

OTLK -2.62%

OVID 1.28%

OYST 0.00%

PALI -3.95%

PASG 0.00%

PBLA -4.76%

PBM -4.74%

PBYI -2.34%

PCSA 0.51%

PCVX 1.12%

PDSB 8.33%

PEPG 4.57%

PGEN 4.55%

PHAR 13.76%

PHAS 0.00%

PHAT -2.26%

PHIO 3.65%

PHIOW 36.47%

PHVS -4.62%

PHXM -5.20%

PIRS -5.56%

PKBO 0.00%

PKBOW 999 900.00%

PLRX 3.28%

PLUR -0.44%

PMN -0.63%

PMVP 4.64%

PNT 0.16%

PPBT 5.78%

PRAX -2.61%

PRDS 0.93%

PRLD 2.88%

PROG -3.47%

PROK -7.60%

PRQR -3.51%

PRTA 0.56%

PRTC -6.90%

PRTG -0.04%

PRTK 1.83%

PRVB 0.00%

PSTI -2.91%

PSTV -11.11%

PSTX -1.08%

PTCT -2.05%

PTE -0.82%

PTGX -0.78%

PTIXW -5.10%

PULM -2.53%

PXMD 0.00%

PYPD -1.97%

PYXS -5.34%

QLGN -8.10%

QNCX 0.71%

QNRX 1.44%

QSI 0.84%

QSIAW 1.20%

QTTB -0.71%

QURE -1.09%

RAIN -1.63%

RANI -0.96%

RAPT 3.18%

RARE -0.45%

RCKT 7.03%

REGN 1.02%

RENB 1.27%

REPL 3.06%

RETA 0.02%

REUN -0.89%

REVB 13.74%

REVBU 3.46%

REVBW 50.29%

RGLS -18.33%

RGNX 6.41%

RIGL 0.65%

RLAY -0.58%

RLMD -0.99%

RLYB 5.48%

RNA 1.69%

RNAC 1.05%

RNAZ 5.27%

RNXT 4.09%

ROIV 2.06%

ROIVW 4.56%

RPHM 0.00%

RPRX 0.74%

RPTX 0.28%

RUBY 2.70%

RVLP -32.05%

RVMD 0.76%

RVMDW 17.51%

RVNC -3.38%

RVPH 2.40%

RVPHW 1.92%

RXDX 0.09%

RXRX 5.54%

RYTM 1.58%

RYZB 0.02%

RZLT 7.85%

SABS 4.23%

SABSW -35.81%

SAGE 3.86%

SANA 0.54%

SAVA -1.10%

SAVAW 0.00%

SBBP 1.52%

SBTX 1.03%

SCNI -6.67%

SCPH 1.24%

SCPS 0.00%

SEEL -2.49%

SEER 1.76%

SELB -8.00%

SESN 7.29%

SGEN -0.07%

SGMO 5.62%

SGMT 6.87%

SGTX -2.56%

SIOX 22.63%

SLDB 2.48%

SLGL 0.59%

SLN 3.61%

SLNO -2.60%

SLRX -3.97%

SLS -0.82%

SMMT 0.88%

SNDX -1.25%

SNGX -2.31%

SNPX 5.67%

SONN -6.53%

SPPI -0.49%

SPRB 5.39%

SPRC -2.42%

SPRO -2.92%

SRNE 15.79%

SRPT 1.95%

SRRA 0.00%

SRRK -0.47%

SRZN 5.26%

STAB 0.00%

STOK 0.70%

STRO -4.95%

STSA 0.00%

STTK -9.50%

SURF -0.93%

SVRA -5.67%

SWTX -0.17%

SYBX 2.01%

SYRS 4.12%

TALS -0.73%

TARA -1.33%

TARS 1.36%

TBPH 0.23%

TCBP -8.11%

TCDA 0.00%

TCON -1.60%

TCRR 0.00%

TCRT -3.84%

TCRX 2.92%

TECH 1.13%

TENX 9.03%

TERN 4.01%

TFFP 9.20%

TGTX 4.31%

THRX 0.12%

TIL -3.68%

TLC 0.00%

TLSA 14.49%

TNGX 0.50%

TNXP -8.46%

TNYA -0.96%

TPST 2.96%

TRDA -4.11%

TRVI -2.22%

TRVN -13.99%

TSHA -10.14%

TSVT 3.76%

TTNP -14.84%

TVTX 6.57%

TYRA 0.35%

UBX 0.36%

UNCY 7.44%

URGN 5.81%

UTHR 0.92%

VACC 11.36%

VALN 12.99%

VAXX -10.53%

VBIV 3.44%

VBLT -8.77%

VCEL 2.64%

VCNX -0.49%

VCYT 1.77%

VERA -2.79%

VERU 9.04%

VERV -0.19%

VIGL 0.52%

VINC -1.38%

VIR 0.22%

VIRI -1.85%

VIRX -5.63%

VKTX -1.18%

VLON -13.04%

VNDA -2.29%

VOR 4.20%

VRCA -4.56%

VRDN 5.09%

VRNA 4.60%

VRPX -4.95%

VRTX 1.33%

VSTM -1.90%

VTGN -3.58%

VTVT 0.00%

VTYX -0.80%

VXRT 5.82%

VYGR -0.43%

VYNE -4.95%

VYNT 7.78%

WINT 7.90%

WVE -0.76%

XBIO -5.83%

XBIT -12.02%

XCUR -3.35%

XENE -0.21%

XERS 0.00%

XFOR 0.00%

XLO 2.47%

XLRN 0.00%

XNCR 1.46%

XOMA 5.64%

XOMAO -0.20%

XOMAP -0.76%

XRTX -2.38%

YMAB 0.83%

ZGNX 0.00%

ZIOP -0.88%

ZLAB 0.97%

ZNTL -3.16%

ZSAN 0.00%

Insider Trading

Date	Person	Action	Amount	type
2024-01-24	Secor Alicia	Sell	46 000	Stock Option (Right to Buy)
2024-01-24	Secor Alicia	Sell	105 000	Stock Option (Right to Buy)
2024-01-24	Geraghty James A	Sell	44 391	Ordinary Shares
2024-01-24	Geraghty James A	Sell	46 000	Stock Option (Right to Buy)
2024-01-24	Geraghty James A	Sell	105 000	Stock Option (Right to Buy)

INSIDER POWER
-42.18
Last 99 transactions
Buy: 13 341 271 \| Sell: 6 351 136

Wolumen Korelacja

Długi: 0.03 (neutral)

Krótki: 0.00 (neutral)

Signal:(85.364) Neutral

Orchard Therapeutics PLC Korelacja

10 Najbardziej pozytywne korelacje

10 Najbardziej negatywne korelacje

Did You Know?

Correlation is a statistical measure that describes the relationship between two variables. It ranges from -1 to 1, where -1 indicates a perfect negative correlation (as one variable increases, the other decreases), 1 indicates a perfect positive correlation (as one variable increases, the other increases), and 0 indicates no correlation (there is no relationship between the variables).

Correlation can be used to analyze the relationship between any two variables, not just stocks. It's commonly used in fields such as finance, economics, psychology, and more.

Orchard Therapeutics PLC Korelacja - Waluta/Towar

-0.61
( weak negative )

-0.75
( moderate negative )

0.48
( neutral )

-0.61
( weak negative )

-0.67
( moderate negative )

0.14
( neutral )

Orchard Therapeutics PLC Finanse

Annual	2022
Przychody:	$6.99M
Zysk brutto:	$4.55M (65.17 %)
EPS:	$-0.610

FY	2022
Przychody:	$6.99M
Zysk brutto:	$4.55M (65.17 %)
EPS:	$-0.610

FY	2021
Przychody:	$1.68M
Zysk brutto:	$1.45M (86.51 %)
EPS:	$-1.170

FY	2020
Przychody:	$2.60M
Zysk brutto:	$1.74M (66.97 %)
EPS:	$-1.530

Financial Reports:

No articles found.

Orchard Therapeutics PLC Options Data

Calls

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Puts

Contract Name	Last Trade Date (EDT)	Strike	Last Price	Bid	Ask	Change	% Change	Volume	Open Interest	Implied Volatility	Strike Date
No data available

Orchard Therapeutics PLC

Orchard Therapeutics plc, a biopharmaceutical company, develops gene therapies for serious and life-threatening rare diseases in the United Kingdom, European Union, and the United States. The company's gene therapy approach seeks to transform a patient's hematopoietic stem cells into a gene-modified cellular drug product to treat the patient's disease through a single administration. It provides Strimvelis, a gammaretroviral-based product for the treatment of adenosine deaminase-severe combined immunodeficiency (ADA-SCID). The company's clinical development products comprise OTL-101 for the treatment of ADA-SCID; OTL-200 to treat metachromatic leukodystrophy; OTL-103 for the treatment of Wiskott-Aldrich syndrome; OTL-102 for X-linked chronic granulomatous disease; and OTL-300 for transfusion-dependent beta-thalassemia. Its preclinical programs include OTL-203 for mucopolysaccharidosis type I, OTL-201 for mucopolysaccharidosis type MPS-IIIA, and OTL-202 for mucopolysaccharidosis type IIIB. It has a strategic collaboration agreement with Pharming Group N.V. for research, development, manufacturing, and commercialization of OTL-105, an investigational ex vivo autologous hematopoietic stem cell gene therapy for the treatment of hereditary angioedema. The company was formerly known as Orchard Rx Limited. Orchard Therapeutics plc was founded in 2015 and is headquartered in London, the United Kingdom.